THEBUSINESSBYTES BUREAU

BENGALURU, JULY 7, 2026

In a significant breakthrough for cancer diagnostics, Reliance Industries Ltd's subsidiary, Strand Life Sciences, has secured an Indian patent for its integrated cell-free DNA (cfDNA)-based platform designed to detect cancer at an early stage through a simple blood test. The technology combines advanced genome sequencing, methylation and fragmentomic analysis, and artificial intelligence to identify the presence of cancer and predict its tissue of origin with high precision.

The newly granted patent covers an end-to-end platform that integrates high-quality genome sequencing, stringent quality control, biologically informed methylation and fragmentomic feature extraction, and machine learning algorithms to enable early cancer detection from a blood sample. The platform is also capable of identifying the tissue of origin, an important factor in guiding further diagnosis and treatment.

A key innovation protected by the patent lies in its ability to accurately capture genome-wide methylation patterns — one of the defining biological signatures of cancer — through genome sequencing with minimal data loss or failure. This significantly enhances the sensitivity of detecting cancer at an early stage, when treatment is most effective.

Cancer continues to pose a major public health challenge in India, with more than 1.5 million new cases estimated every year. A substantial proportion of patients are diagnosed only after the disease has progressed to advanced stages, limiting treatment options and reducing survival outcomes. Early detection has the potential to transform cancer care by enabling timely intervention.

The company noted that current guideline-based screening programmes cover only a limited range of cancers and are difficult to scale across large populations. With the declining cost of genome sequencing, the patented platform has the potential to facilitate population-scale cancer screening without requiring significant expansion of local healthcare infrastructure.

"Early detection is an increasingly relevant topic as cancer is becoming one of India's greatest public health challenges. This patent reflects our commitment to developing scientifically rigorous, AI-enabled liquid biopsy technologies that can help detect cancer earlier from a simple blood sample. We believe this innovation represents an important step towards making precision cancer screening more accurate, scalable, and accessible," said Ramesh Hariharan, CEO, Strand Life Sciences.

The patent further strengthens Strand Life Sciences' intellectual property portfolio in the fast-evolving field of liquid biopsy and reinforces the company's long-term strategy of developing integrated, AI-enabled molecular technologies for early cancer detection and precision oncology. The development is expected to bolster its position in advancing next-generation cancer diagnostics and expanding access to precision healthcare solutions.